Computations in the brain that mediate behavior occur at multiple spatial and temporal scales. Information is integrated in the brain within single cells, which are interconnected in dense local circuits, which are in turn, incorporated in larger networks spanning many brain regions. A critical challenge for modern neuroscience is to study the brain across these multiple spatial scales. Traditionally, the modalities used to observe activities at one level do not scale to the next level without loss of signal fidelity or information. In our laboratory, we are developing technologies to bridge some of these experimental scales - seeking to both sense and manipulate neural activity with great precision.
Technologies for large scale high resolution neural interfacing
Robotics for single neuron recordings
Robotics for single cell microinjection
Technologies for non-invasive neuromodulation